Wofufuza wina wa ku France wadziwitsa anthu za kuopsa kwa singano zakuthwa m'ma laboratories pambuyo pa ngozi yoopsa yokhudza kutuluka kwa madzi osungunuka nthawi zonse. Tsopano akupempha kuti pakhale njira zina zosinthira singano kuti zisamutsire zosungunulira kapena zobwezeretsanso kuti ziwongolere chitetezo cha ma laboratories.
Mu June 2018, wophunzira wazaka 22 Nicolas anali kugwira ntchito mu labotale ya Sebastien Vidal ku University of Lyon 1. Anathira sirinji ya dichloromethane (DXM) mu botolo ndipo mwangozi anabaya chala chake. Vidal anawerengera kuti madontho awiri kapena osachepera 100 microliters a DXM anatsala mu singano ndipo analowa m'chala.
Zithunzi zingapo zikuwonetsa zomwe zinachitika pambuyo pake - nkhani ya magaziniyi ikuchenjeza kuti ena angavutike ndi zithunzizo (pansipa). Patatha mphindi 15 kuchokera pamene anabayidwa ndi singano, Nicolas adapanga malo ofiirira pa chala chake. Patatha maola awiri, m'mphepete mwa ma plaque ofiirira adayamba kuda, zomwe zikusonyeza kuti maselo adayamba kufa. Panthawiyi, Nicholas adadandaula kuti zala zake zinali zotentha ndipo sakanatha kuzisuntha.
Nicholas anafunika opaleshoni yadzidzidzi kuti apulumutse chala chake. Madokotala a opaleshoni, omwe poyamba ankaganiza kuti ayenera kudulidwa, anachotsa khungu lakufa lozungulira bala lobayidwa ndi kubwezeretsanso chalacho pogwiritsa ntchito chogwirira cha khungu kuchokera m'dzanja la Nicholas. Pambuyo pake dokotalayo anakumbukira kuti pazaka 25 akugwira ntchito m'zipinda zadzidzidzi, sanaonepo kuvulala kotereku.
Zala za Nicholas tsopano zabwerera mwakale, ngakhale kuti kusewera gitala kwake kunadwala matenda a necrosis omwe anawononga mitsempha yake, zomwe zinafooketsa mphamvu zake ndi luso lake.
DCM ndi imodzi mwa zinthu zosungunulira zachilengedwe zomwe zimagwiritsidwa ntchito kwambiri m'ma laboratories opanga mankhwala. DCM Injury Information ndi Material Safety Data Sheet (MSDS) zimapereka tsatanetsatane wa momwe munthu angakhudzire maso, khungu, kumwa ndi kupuma, koma osati pamene akumwa jakisoni, Vidal adatero. Pa kafukufukuyu, Vidal adapeza kuti chochitika chofananacho chinachitika ku Thailand, ngakhale kuti mwamunayo adadzibaya dala ndi ma mililita awiri a dichloromethane, zomwe zotsatira zake zidanenedwa kuchipatala cha Bangkok.
Milandu iyi ikusonyeza kuti mafayilo a MSDS ayenera kusinthidwa kuti aphatikizepo zambiri zokhudzana ndi ma parenterals, anatero Vidal. "Koma mkulu wanga wa chitetezo ku yunivesite anandiuza kuti kusintha mafayilo a MSDS kungatenge nthawi yayitali ndipo kumafuna zambiri zambiri kuti zisonkhanitsidwe." Izi zinaphatikizapo maphunziro atsatanetsatane a nyama kuti abwerezenso ngoziyo, kusanthula kuwonongeka kwa minofu, ndi kuwunika kwachipatala.
Zala za ophunzira m'magawo osiyanasiyana atalandira jakisoni wa methylene chloride pang'ono mwangozi. Kuchokera kumanzere kupita kumanja, mphindi 10-15 pambuyo povulala, kenako maola awiri, maola 24 (atachitidwa opaleshoni), masiku awiri, masiku asanu, ndi chaka chimodzi (zonsezi zili m'munsimu)
Popeza palibe chidziwitso chokhudza kukhazikitsidwa kwa DCM, Vidal akuyembekeza kuti nkhaniyi idzafalitsidwa kwambiri. Ndemanga zake ndi zabwino. Iye anati chikalatacho [chafalitsidwa kwambiri]. "Akuluakulu a chitetezo ochokera ku mayunivesite ku Canada, US ndi France adandiuza kuti aphatikiza nkhaniyi m'maphunziro awo. Anthu adatiyamikira chifukwa chogawana nkhaniyi. Ambiri sanafune kuyankhula za nkhaniyi poopa kulengezedwa molakwika [kwa bungwe lawo] Koma mabungwe athu akhala akuthandiza kwambiri kuyambira pachiyambi ndipo akupitilizabe kuthandiza."
Vidal akufunanso kuti gulu la asayansi ndi ogulitsa mankhwala apange njira zotetezeka komanso zida zina zogwiritsira ntchito nthawi zonse monga kusamutsa mankhwala. Lingaliro limodzi ndikugwiritsa ntchito singano "yolunjika bwino" kuti tipewe mabala obowoka. "Panopa alipo, koma nthawi zambiri timagwiritsa ntchito singano zolunjika mu organic chemistry chifukwa timafunika kuyambitsa zosungunulira kudzera mu zotchingira rabara kuti titeteze mitsempha yathu yoyankhira ku mpweya/chinyezi chakunja. Singano "yolunjika" singadutse mu zotchingira rabara. Ili si funso losavuta, koma mwina kulephera kumeneku kubweretsa malingaliro abwino.
Alain Martin, manejala wa zaumoyo ndi chitetezo ku Dipatimenti ya Chemistry ya University of Strathclyde, anati sanaonepo ngozi yotereyi. “Mu labu, nthawi zambiri ma syringe okhala ndi singano amagwiritsidwa ntchito, koma ngati kulondola n’kofunika, ndiye kuti kugwiritsa ntchito ma micropipettes kungakhale njira yotetezeka,” akuwonjezera, kutengera maphunziro, monga kusankha nsonga ndi kugwiritsa ntchito ma pipettes molondola. “Kodi ophunzira athu akuphunzitsidwa momwe angagwiritsire ntchito singano moyenera, momwe angaikire ndikuchotsa singano?” anafunsa. “Kodi pali amene akuganiza kuti ndi chiyani china chomwe chingagwiritsidwe ntchito? Mwina ayi.
2 K. Sanprasert, T. Thangrongchitr ndi N. Krairojananan, Asia. Paketi. J. Med. Toxicology, 2018, 7, 84 (DOI: 10.22038/apjmt.2018.11981)
Ndalama zokwana madola 210 miliyoni kuchokera kwa wamalonda wa Moderna komanso wosunga ndalama Tim Springer kuti athandizire kafukufuku yemwe akuchitika
Kuphatikiza kwa kuyesa kwa X-ray diffraction ndi ma simulations kukuwonetsa kuti kuwala kwa laser kwamphamvu kumatha kusintha polystyrene.
© Royal Society of Chemistry document.write(new Date().getFullYear()); Nambala yolembetsa ya bungwe lothandiza anthu: 207890